40359-34-0

Usage

Uses

Used in Flavor and Fragrance Industry:
Methyl (2-Formylphenoxy) acetate is used as a flavoring agent and fragrance ingredient for its sweet, fruity scent profile, similar to honey. It is incorporated into various products to enhance their aroma and appeal to consumers.
Used in Organic Synthesis:
Methyl (2-Formylphenoxy) acetate is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of a wide range of derivatives, making it a valuable building block in the development of new chemical entities.
Caution:
As with many chemicals, Methyl (2-Formylphenoxy) acetate should be used with caution due to potential toxicity or safety concerns that may not have been fully investigated. Proper handling, storage, and disposal protocols should be followed to minimize any risks associated with its use.

InChI:InChI=1/C10H10O4/c1-13-10(12)7-14-9-5-3-2-4-8(9)6-11/h2-6H,7H2,1H3

Upstream product

• 67-56-1 methanol 
• 6280-80-4 2-Formylphenoxyacetic acid 
• 89-95-2 2-methyl-benzyl alcohol 
• 96-34-4 methyl chloroacetate 
• 90-02-8 salicylaldehyde 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 1646-27-1 methyl benzofuran-2-carboxylate 
• 6280-80-4 2-Formylphenoxyacetic acid 
• 51336-24-4 4-(2-methoxycarbonylmethoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester 
• 1448677-74-4 3-((Z)-((Z)-5-(2-(2-methoxy-2-oxoethoxy)benzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid 

Relevant academic research and scientific papers

Bifunctional building blocks in the Ugi-azide condensation reaction: A general strategy toward exploration of new molecular diversity

1,5-Disubstituted tetrazoles are an important drug-like scaffold known for their ability to mimic the cis-amide bond conformation. The scaffold is readily accessible via substitution of the carboxylic acid component of the Ugi multi-component reaction (MCR) with TMSN3 in what is herein denoted the Ugi-azide reaction. This full paper presents a concise, novel, general strategy to access a plethora of new heterocylic scaffolds utilizing tethered aldo/keto-acids/esters in the Ugi-azide reaction followed by a ring closing event that generates novel highly complex bis-heterocyclic lactam-tetrazoles. The Royal Society of Chemistry.

Titanium mediated olefination of aldehydes with α-haloacetates: An exceptionally stereoselective and general approach to (Z)-α-haloacrylates

An exceptionally stereoselective and general synthesis of (Z)-α-haloacrylates, ready to undergo various synthetic transformations, has been demonstrated from α-haloacetates and aldehydes in a one-pot manner via the titanium-enolate based asymmetric aldol

Potash alum [KAL(SO4)2.12H2O] catalysed esterification of formylphenoxyaliphatic acids

A convenient and clean procedure for esterification is reported. Direct condensation of formylphenoxyaliphatic acids with low to high boiling alcohols catalysed by potash alum gave moderate to good yields. This catalyst could be recovered and reused without substantial loss in its catalytic activity and the methodology could be used for a range of closely related substrates.

Novel Compounds

The present invention provides compounds of formula (I): wherein Ra, Rb, Rc, R1, R2, R3, X1, Y1, Z1, A, n and m are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Compounds for treatment of cardiac arrhythmia synthesis, and methods of use

The subject invention pertains to novel compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making the novel compounds. The novel compounds are rapidly metabolized analogs of amiodarone, having the distinct and advantageous characteristic of being metabolized to a less lipophilic compound. The new compounds can have particular utility for treating life-threatening ventricular tachyarrhythmias, especially in patients with congestive heart failure (CHF). The product can also provide effective management for ventricular arrhythmias and supraventricular arrhythmias, including atrial fibrillation and re-entrant tachyarrhythmias involving accessory pathways.

Synthesis and antibacterial activity of some novel 4-oxo-1,3-thiazolidines, 2-oxoazetidines and 5-oxoimidazolines: Part VI

Several methyl 2-{2-[4-oxo-3-(arylcarbonylamino)-1,3-thiazolidin-2-yl] phenoxy}acetates 3a-h, methyl 2-{2-[3-chloro-4-oxo-1-(arylcarbonylamino)azetidin-2-yl]phenoxy}acetates 4a-e, methyl 2-(2-{[5-oxo-2-phenyl-1-(arylcarbonylamino)-2-imidazolin-4-ylidene]methyl}p henoxy)acetates 6a-i and methyl 2-{2-[(5-oxo-2-phenyl-1-{[(arylamino)thioxomethyl]-amino}-2-imidazolin-4-y lidene)methyl] phenoxy} acetates 7a-p have been synthesized. All the synthesized compounds have been evaluated for their in Vitro growth inhibitory activity against several microbes like E. coli, S. aureus and Salmonella typhi para A. The structures of these compounds have been established on the basis of elemental analysis and spectral data.

Compound for treatment of cardiac arrhythmia, synthesis, and methods of use

Described is a novel compound and method, useful for treatment of cardiac arrhythmias, especially useful in patients with congestive heart failure (CHF). A process for synthesizing the novel compound is also described.

Compound for treatment of cardiac arrhythmia, synthesis, and methods of use

Described is a novel compound and method, useful for treatment of cardiac arrhythmias, especially useful in patients with congestive heart failure (CHF). A process for synthesizing the novel compound is also described.

Synthesis of Aryloxy Analogues of Arachidonic Acid via Wittig and Palladium Catalysed Cross-coupling Reactions

The synthesis of o- and p-phenoxy analogues of arachidonic acid is described.In particular, the Wittig olefination reaction of hydroxy and alkyloxy benzaldehydes has been investigated and the products shown to be highly dependent on the solvent used.E/Z isomer control was difficult to achieve in most cases, although there was a tendency towards Z-isomer formation in dimethyl sulphoxide compared to tetrahydrofuran, particularly for the phenolic compounds.Specific Z-isomer formation was achieved by the partial reduction of alkynes derived from appropriately protected bromophenols via Heck or palladium catalysed cross-coupling reactions.