403621-52-3

Upstream product

• 164732-67-6 6-Vinyl-3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester 
• 403621-50-1 C₂₇H₃₀O₄ 
• 403621-36-3 C₃₂H₄₀O₅Si 
• 403621-49-8 C₃₂H₄₂O₅Si 
• 403621-32-9 {1-[(1R,3aS,7aS)-1-(4-Methoxy-phenyl)-7a-methyl-1,4,5,6,7,7a-hexahydro-1,3a-etheno-inden-9-yl]-vinyloxy}-trimethyl-silane 
• 403621-31-8 1-[(1R,3aS,7aS)-1-(4-Methoxy-phenyl)-7a-methyl-1,4,5,6,7,7a-hexahydro-1,3a-etheno-inden-9-yl]-ethanone 

Downstream Products

• 403621-31-8 1-[(1R,3aS,7aS)-1-(4-Methoxy-phenyl)-7a-methyl-1,4,5,6,7,7a-hexahydro-1,3a-etheno-inden-9-yl]-ethanone 
• 160695-09-0 (S)-3-(4-Methoxy-phenyl)-3a-methyl-4,5,6,7-tetrahydro-3aH-indene 

Relevant academic research and scientific papers

Enantiopure polycycles by sequential cycloadditions

The enolsilyl ether 2, generated from butynone adduct 3, which is easily available from the enantiomerically pure cyclopentadiene 1, proved to be a general building block for polycyclic anellation products to cyclohexenone. After proper adjustment of functional groups in the cycloadducts by means of high pressure Diels-Alder cycloadditions, the thermal retro-process provided routes to various enantiopure alicyclic and heterocyclic target compounds in high yields.