403647-94-9

Upstream product

• 403647-92-7 2-[(E)-2-(3,4-Diacetoxy-phenyl)-vinyl]-8-methoxy-quinoline-7-carboxylic acid methyl ester 
• 406479-53-6 8-methoxy-2-methyl-quinoline-7-carboxylic acid methyl ester 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 403647-93-8 2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-methoxy-quinoline-7-carboxylic acid methyl ester 

Downstream Products

• 403647-96-1 (2-{2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinyl}-8-methoxy-quinolin-7-yl)-oxo-thioacetic acid S-methyl ester 
• 403647-95-0 1-(2-{2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinyl}-8-methoxy-quinolin-7-yl)-2,2,2-tris-methylsulfanyl-ethanone 

Relevant academic research and scientific papers

HIV-1 replication inhibitors of the styrylquinoline class: Incorporation of a masked diketo acid pharmacophore

A novel variant of HIV-1 replication inhibitors of the styrylquinoline class, bearing an α-keto acid appendage at C-7, has been synthesized. Though completely inactive in in vitro experiments against HIV-1 integrase, this compound exhibited a significant antiviral activity (IC50 = 10 μM).