403670-55-3Relevant articles and documents
A new route to butane-1,2-diacetals and the development of alternative substitution patterns to facilitate differential protection of the products
Ley,Michel
, p. 1793 - 1795 (2001)
The utility of 2,3-dialkoxybutan-1,3-dienes as reagents for the protection of vicinal diols and α-hydroxy acids as their corresponding 1,2-diacetals is demonstrated together with their later deprotection under mild reaction conditions.
Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to α-hydroxyacid and amide derivatives
Ley, Steven V.,Diez, Elena,Dixon, Darren J.,Guy, Richard T.,Michel, Patrick,Nattrass, Gillian L.,Sheppard, Tom D.
, p. 3608 - 3617 (2007/10/03)
The preparation of butane-2,3-diacetal protected glycolic acid and related systems is described together with highly selective alkylation reactions of (R,R) and (S,S) butanediacetal protected glycolic acid. These compounds are readily deprotected to give