403694-73-5Relevant academic research and scientific papers
De novo synthesis of novel bacterial monosaccharide fusaminic acid
Wei, Ruohan,Liu, Han,Li, Xuechen
, p. 420 - 431 (2019/03/29)
Fusobacterium nucleatum is an oral bacteria related to various types of diseases. As Gram-negative bacteria, lipopolysaccharide (LPS) of Fusobacterium nucleatum could be a potential virulence factor. Recently, the structure of O-antigen in LPS of Fusobact
RCM mediated synthesis of macrosphelides I and G
Sharma, Gangavaram V.M.,Veera Babu, Kagita
, p. 2175 - 2184 (2008/02/11)
The total synthesis of 16-membered macrolides, macraosphelides I and G, has been achieved starting from ethyl-(S)-lactate and (S)-malic acid. A combination of Jacobsen's hydrolytic kinetic resolution and Sharpless epoxidation is used for the creation of two stereogenic centres, while Yamaguchi esterification and ring-closing metathesis strategies were used for the construction of the lactone ring.
Asymmetric total synthesis of (+)-brefeldin A from (S)-lactate by triple chirality transfer process and nitrile oxide cycloaddition
Kim, Deukjoon,Lee, Jongkook,Phil, Jong Shim,Joong, Inn Lim,Jo, Hyunil,Kim, Sanghee
, p. 764 - 771 (2007/10/03)
A novel synthesis of (+)-brefeldin A (1) has been accomplished on the basis of triple chirality transfer methodology, intramolecular ester enolate alkylation, and both intra- and intermolecular nitrile oxide cycloaddition strategies.
