4038-17-9

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 
• 855462-38-3 4-hydroxy-2,3',4'-trimethoxy-benzophenone 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 151-10-0 1,3-Dimethoxybenzene 
• 857227-41-9 3-(3-methoxy-4-veratroyl-phenoxy)-propionic acid 
• 93-07-2 Veratric acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 876488-84-5 3-(3-methoxy-phenoxy)-propionic acid ethyl ester 

Downstream Products

• 4532-65-4 2,4,3',4'-tetramethoxy-thiobenzophenone 
• 1582229-70-6 4-[azido(2,4-dimethoxyphenyl)methyl]-1,2-dimethoxybenzene 
• 1582229-73-9 (2,4-dimethoxyphenyl)(3,4-dimethoxyphenyl)methanamine hydrochloride 
• 330675-44-0 1-(2,4-dimethoxyphenyl)-1-(3,4-dimethoxyphenyl)-2-propyn-1-ol 

Relevant academic research and scientific papers

One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems

A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.

Synthesis and carbonic anhydrase isoenzymes i and II inhibitory effects of novel benzylamine derivatives

Synthesis and carbonic anhydrase inhibitory properties of novel diarylmethylamines 22-25 and sulfonamide derivatives 26-28 were investigated. Acylation of methoxy-substituted benzenes with benzene carboxylic acids, reduction of ketones with NaBH4, conversion of alcohols to azides, Pd-C catalyzed hydrogenation of azides afforded title compounds 22-25. Compounds 22, 24 and 25 were converted to sulfonamide derivatives 26-28 with MeSO2Cl. The inhibitory effects of novel benzylamine derivatives 22-28 were tested on human carbonic anhydrase (hCA, EC 4.2.1.1) isozymes hCA I and II. The results demonstrated that compound 28 was found to be the best inhibitor against both hCA I (Ki: 3.68 μM) and hCA II (Ki: 9.23 μM).

3,3-bis(aryl)-5-((N-(un)substituted)amido)naphthopyrans, their preparation, compositions and (co)polymer matrices containing them

The object of the present invention is novel naphthopyran compounds as well as the compositions and (co)polymer matrices containing them. Said compounds have interesting photochromic properties. Another object of the present invention is a method of preparing said novel compounds.