4038-70-4 Usage
Uses
Used in Neuroscientific Research:
MPTP is utilized as a neurotoxin in animal studies for the purpose of inducing Parkinson's disease-like symptoms. It is used as a research tool to investigate the underlying mechanisms of the disease and to test potential therapeutic interventions. 1-Methyl-4-phenyl-3-propyl-1H-pyrazol-5-aMine causes damage to dopaminergic neurons in the brain, which is a characteristic feature of Parkinson's disease.
Used in Toxicological Studies:
MPTP is employed in toxicological research to understand the effects of neurotoxins on the central nervous system. This helps in the development of safety guidelines and protective measures for individuals who may be exposed to similar substances in occupational or environmental settings.
Used in Drug Development:
Although MPTP is not approved for human use, its properties are studied in the context of drug development. Researchers aim to understand how its toxic effects can be mitigated or reversed, potentially leading to the discovery of new treatments for Parkinson's disease and other neurodegenerative conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 4038-70-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,3 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4038-70:
(6*4)+(5*0)+(4*3)+(3*8)+(2*7)+(1*0)=74
74 % 10 = 4
So 4038-70-4 is a valid CAS Registry Number.
4038-70-4Relevant academic research and scientific papers
Oxidative aromatic C-N bond formation: Convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization
Zheng, Zisheng,Tang, Lina,Fan, Yanfeng,Qi, Xiuxiang,Du, Yunfei,Zhang-Negrerie, Daisy
experimental part, p. 3714 - 3725 (2011/06/27)
A variety of functionalized N-amino-3-nitrile-indole derivatives are obtained via an intramolecular hetero-cyclization of 2-aryl-3-substituted hydrazono-alkylnitriles using FeBr3 as a single electron oxidant. This approach allows the N-moiety on the side-chain to be annulated to the benzene ring during the final synthetic step via direct oxidative aromatic C-N bond formation.
