4038-92-0

Basic information

• Product Name: 1-(2-DIETHYLAMINOETHYL)PIPERAZINE
• Synonyms: RARECHEM AH CK 0085;1-(2-DIETHYLAMINOETHYL)PIPERAZINE;Diethylaminoethylpiperazine;1-[2-(Diethylamino)ethyl]piperazine 97%;DIETHYL-(2-PIPERAZIN-1-YL-ETHYL)-AMINE;1-[2-(DIETHYLAMINO)-ETHYL]-PIPERAZINE >98%;N,N-Diethyl-2-(piperazin-1-yl)ethylamine, N-[2-(piperazin-1-yl)ethyl]diethylamine;1-[2-(Diethylamino)ethyl]piperazine97%
• CAS NO: 4038-92-0
• Molecular Formula: C₁₀H₂₃N₃
• Molecular Weight: 185.31
• Mol File: 4038-92-0.mol

Chemical Properties

• Boiling Point: 84 °C
• Flash Point: 93.4 °C
• Appearance: /
• Density: 0.906 g/cm³
• Vapor Pressure: 0.0289mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 1-(2-DIETHYLAMINOETHYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-DIETHYLAMINOETHYL)PIPERAZINE(4038-92-0)
• EPA Substance Registry System: 1-(2-DIETHYLAMINOETHYL)PIPERAZINE(4038-92-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 4038-92-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Diethylaminoethyl)piperazine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of drugs with diverse therapeutic applications. Its structural features allow for the creation of compounds that can target specific biological pathways or receptors, enhancing the effectiveness of medications.
Used in Organic Synthesis:
In the realm of organic synthesis, 1-(2-Diethylaminoethyl)piperazine serves as a versatile building block for creating compounds with a wide array of pharmacological activities. Its ability to form various chemical bonds and its compatibility with different chemical groups make it an essential component in the synthesis of organic compounds with potential applications in medicine, agriculture, and other fields.
Used in Agrochemical Production:
1-(2-Diethylaminoethyl)piperazine is also utilized as a precursor in the production of agrochemicals, where it can be incorporated into the structures of pesticides, herbicides, or other agricultural chemicals. Its role in these compounds can enhance their effectiveness in protecting crops or managing pests, contributing to increased agricultural productivity.
Used in Specialty Chemicals:
1-(2-DIETHYLAMINOETHYL)PIPERAZINE finds application in the development of specialty chemicals, where its unique properties can be tailored to meet specific industrial needs. This includes uses in the creation of dyes, coatings, or other chemical products that require the unique structural and functional attributes of 1-(2-Diethylaminoethyl)piperazine.

InChI:InChI=1/C10H23N3/c1-3-12(4-2)9-10-13-7-5-11-6-8-13/h11H,3-10H2,1-2H3

Upstream product

• 859298-76-3 1-(2-diethylamino-ethyl)-4-(toluene-4-sulfonyl)-piperazine 
• 110-85-0 piperazine 
• 208167-83-3 tert-butyl 4-(2-chloroethyl)tetrahydro-1(2H)-pyrazinecarboxylate 
• 77279-24-4 tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 1620922-48-6 tert-butyl 4-(2-(diethylamino)ethyl)piperazine-1-carboxylate 

Downstream Products

• 773034-50-7 Acetic acid 4-[4-(2-diethylamino-ethyl)-piperazine-1-carbonyl]-phenyl ester 
• 183591-58-4 [4-(2-Diethylamino-ethyl)-piperazin-1-yl]-(4-hydroxy-phenyl)-methanone 
• 959847-19-9 [4-(2-diethylamino-ethyl)-piperazin-1-yl]-[4-methyl-1-(4-methylbenzyl)-3-p-tolyl-1H-pyrrol-2-yl]-methanone 
• 54997-97-6 5-{4-[2-(diethylamino)ethyl]piperazin-1-yl}-2-nitroaniline 

Relevant articles and documents

Natural product-based design, synthesis and biological evaluation of anthra[2,1-d]thiazole-6,11-dione derivatives from rhein as novel antitumour agents

Two series of novel 2-substituted 5,7-dihydroxyanthra[2,1-d]thiazole-6,11- dione derivatives from natural rhein were designed, synthesized and evaluated for their antitumour activities against human cancer cell lines A549 and HeLa in vitro.

Synthesis of 1-(4-acyloxybenzoyloxyacetyl)-4-alkylpiperazines and 1-(4-acyloxybenzoyl)-4-alkylpiperazines as inhibitors of chymotrypsin

Sixteen new esters and amides of 4-acyloxybenzoic acids were prepared and screened as chymotrypsin inhibitors. Inhibiting activities on chymotrypsin differed markedly (>100-0.008 μM). Compounds which contained the 4-benzoyloxyacetyl moiety showed considerably higher activity then dacyloxybenzamides. Compounds 1c and 11f are also weak trypsin inhibitors.