403821-75-0Relevant academic research and scientific papers
Purine and Guanine Thioglycoside Analogs: Novel Synthesis of a New Class of Pyrazolo[1,5-a][1,3,5]Triazine-4-Thioglycoside Derivatives under Microwave Activation
Elgemeie, Galal,Abu-Zaied, Mamdouh
, p. 834 - 847 (2015)
A first microwave-assisted synthesis of a new class of novel purine thioglycoside analogues from readily available starting materials has been described. The key step of this protocol is the formation of sodium pyrazolo[1,5-a][1,3,5]triazine-4-thiolates via condensation of 5-amino-1H-pyrazoles with sodium cyanocarbonimidodithioate salt under microwave irradiation, followed by coupling with halo sugars to give the corresponding purine thioglycoside analogues. Further studies on the application of this method for the synthesis of other highly functionalized biologically active glycosides are underway.
The reaction of dimethyl N-cyanodithioiminocarbonate with amino- and oxo-azoles: A new general synthesis of methylsulfanylazoloazines
Elgemeie,Sood
, p. 439 - 441 (2007/10/03)
A novel and efficient method for the synthesis of a new variety of methylsulfanylazoloazines by the reaction of dimethyl N-cyanodithioiminocarbonate with diazoles containing amino and active methylene functions. The synthetic potential of the method is demonstrated.
