403860-27-5Relevant articles and documents
Design and synthesis of novel diamide derivatives of glycine as antihyperglycemic agents
Sharma, Radhika,Soman, Shubhangi S.
supporting information, p. 1307 - 1317 (2016/08/16)
DPP-4 inhibition is one of the most extensively explored approaches for the management of type 2 diabetes (T2D). Most DPP-4 inhibitors in the market contain a proline mimetic active pharmacophore. Herein, we report the design, synthesis, and preliminary e
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic
Balboni, Gianfranco,Fiorini, Stella,Baldisserotto, Anna,Trapella, Claudio,Sasaki, Yusuke,Ambo, Akihiro,Marczak, Ewa D.,Lazarus, Lawrence H.,Salvadori, Severo
experimental part, p. 5109 - 5117 (2009/08/16)
Some reference opioids containing the Dmt-Tic pharmacophore, especially the δ agonists H-Dmt-Tic-GlyNH-Ph (1) and H-Dmt-TiC-NH-(S)CH(CH 2-COOH)-Bid (4) (UFP-512) were evaluated for the influence of the substitution of Gly with aspartic acid, it