40391-43-3Relevant academic research and scientific papers
Br?nsted Acid Enabled Nickel-Catalyzed Hydroalkenylation of Aldehydes with Styrene and its Derivatives
Han, Xing-Wang,Zhang, Tao,Zheng, Yan-Long,Yao, Wei-Wei,Li, Jiang-Fei,Pu, You-Ge,Ye, Mengchun,Zhou, Qi-Lin
, p. 5068 - 5071 (2018)
A Br?nsted acid enabled nickel-catalyzed hydroalkenylation of aldehydes and styrene derivatives has been developed. The Br?nsted acid acts as a proton shuttle to transfer a proton from the alkene to the aldehyde, thereby leading to an economical and byproduct-free coupling. A series of synthetically useful allylic alcohols were obtained through one-step reactions from readily available styrene derivatives and aliphatic aldehydes in up to 88 % yield and with high linear selectivity.
