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(±)-2-Fluoro-3-phenylpropanamide is a chiral organic compound with the molecular formula C9H10FNO. It is a derivative of propanamide, featuring a fluorine atom at the 2-position and a phenyl group at the 3-position. (±)-2-fluoro-3-phenylpropanamide is known for its potential applications in medicinal chemistry, particularly as a building block for the synthesis of various pharmaceuticals and agrochemicals. Due to its chiral nature, it exists as a mixture of two enantiomers, which can have different biological activities. The compound's properties, such as its reactivity and solubility, can be influenced by the presence of the fluorine atom, which can also affect its metabolic stability and pharmacokinetics. Research on (±)-2-fluoro-3-phenylpropanamide and its derivatives may lead to the development of new drugs with improved efficacy and selectivity.

404-16-0

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404-16-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 404-16-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 404-16:
(5*4)+(4*0)+(3*4)+(2*1)+(1*6)=40
40 % 10 = 0
So 404-16-0 is a valid CAS Registry Number.

404-16-0Downstream Products

404-16-0Relevant academic research and scientific papers

Organomediated Enantioselective 18F Fluorination for PET Applications

Buckingham, Faye,Kirjavainen, Anna K.,Forsback, Sarita,Krzyczmonik, Anna,Keller, Thomas,Newington, Ian M.,Glaser, Matthias,Luthra, Sajinder K.,Solin, Olof,Gouverneur, Véronique

, p. 13366 - 13369 (2015)

The first organomediated asymmetric 18F fluorination has been accomplished using a chiral imidazolidinone and [18F]N-fluorobenzenesulfonimide. The method provides access to enantioenriched 18F-labeled α-fluoroaldehydes (>90 % ee), which are versatile chiral 18F synthons for the synthesis of radiotracers. The utility of this process is demonstrated with the synthesis of the PET (positron emission tomography) tracer (2S,4S)-4-[18F]fluoroglutamic acid.

Simple synthesis of optically active 2-fluoropropanoic acid and analogs of high enantiomeric purity

Fritz-Langhals, Elke,Schuetz, Gabi

, p. 293 - 296 (2007/10/02)

A very simple synthesis of optically active 2-fluoropropanoic acid 1 (R=CH3, R′=H) and analogs of high enantiomeric purity was developed using the sulfonates 2 of the corresponding optically active 2-hydroxycarboxylic esters and potassium fluor

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