107365-23-1Relevant articles and documents
Direct organocatalytic α-fluorination of aldehydes and ketones
Enders, Dieter,Hüttl, Matthias R. M.
, p. 991 - 993 (2005)
The first organocatalytic direct α-fluorination of aldehydes and ketones employing Selectfluor {1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2. 2]octane bis(tetrafluoroborate)} as the fluorine source is reported. (S)-Proline and related derivatives act as organocatalysts to give the corresponding α-fluoroaldehydes and α-fluoroketones in moderate to good yields (47-78%). The asymmetric inductions are still low (ee ≤ 36%).
Diastereoselective nucleophilic addition to aldehydes with polar α- And α,β-substituents
Borg, Tessie,Danielsson, Jakob,Mohiti, Maziar,Restorp, Per,Somfai, Peter
supporting information; experimental part, p. 2022 - 2036 (2011/10/31)
The stereoselectivities obtained in Lewis acid-promoted Mukaiyama aldol additions and Sakurai allylations of mono-, and syn- and anti-disubstituted aldehydes possessing various polar α- and β-substituents under non-chelating conditions are presented. The
PREPARATION OF α-FLUOROALDEHYDES AND α-FLUOROKETONES USING DILUTE FLUORINE
Purrington, Suzane T.,Lazaridis, Nicholas V.,Bumgardner, Carl L.
, p. 2715 - 2716 (2007/10/02)
Fluorination of silyl enol ethers with 5percent F2 in N2 at -78 deg C in Freon 11 results in the formation of α-fluoroketones and α-fluoroaldehydes.
