4040-08-8

Basic information

• Product Name: N-butyl-[1,3,5]triazine-2,4-diamine
• Synonyms: N-butyl-[1,3,5]triazine-2,4-diamine
• CAS NO: 4040-08-8
• Molecular Formula: C7H13N5
• Molecular Weight: 167
• Mol File: 4040-08-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 144 °C
• Boiling Point: 362.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.191±0.06 g/cm3(Predicted)
• PKA: 4.20±0.10(Predicted)
• CAS DataBase Reference: N-butyl-[1,3,5]triazine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl-[1,3,5]triazine-2,4-diamine(4040-08-8)
• EPA Substance Registry System: N-butyl-[1,3,5]triazine-2,4-diamine(4040-08-8)

Safety Data

• Hazardous Substances Data: 4040-08-8(Hazardous Substances Data)

Upstream product

• 931-86-2 5-azacytosine 
• 109-73-9 N-butylamine 
• 692-13-7 buformin 
• 109-94-4 formic acid ethyl ester 
• 77287-34-4 formamide 
• 37019-19-5 desethylterbuthylazine 

Relevant articles and documents

The scope and mechanism of phosphonium-mediated SNAr reactions in heterocyclic amides and ureas

(Chemical Equation Presented) An efficient "one-step" synthesis of cyclic amidines and guanidines has been developed. Treatment of cyclic amides and ureas with benzotriazol-l-yloxytris(dimethylamino)phosphonium hexafluorophosphate (BOP), base, and nitrogen nucleophiles leads to the formation of the corresponding cyclic amidines and guanidines, typically in good to excellent yields. This method has also been used to prepare heteroaryl ethers and thioethers using phenol and thiophenol nucleophiles. Time course NMR and HPLC-MS studies have facilitated explicit characterization of the proposed intermediates (the phosphonium salt and HOBt adduct); the data reveal a stepwise reaction pathway.

Potential antiviral agents: N-acyl derivatives of the s-triazine

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