404033-91-6Relevant academic research and scientific papers
Pd0-catalyzed intramolecular α-arylation of sulfones: Domino reactions in the synthesis of functionalized tetrahydroisoquinolines
Solé, Daniel,Pérez-Janer, Ferran,Mancuso, Raffaella
, p. 4580 - 4584 (2015)
A new strategy for the synthesis of tetrahydroisoquinolines based on the Pd0-catalyzed intramolecular a-arylation of sulfones is reported. The combination of this Pd-catalyzed reaction with intermolecular Michael and aza-Michael reactions allows the development of two- and three-step domino processes to synthesize diversely functionalized scaffolds from readily available starting materials.
Synthesis of substituted aziridines via intramolecular reactions of β-N-chloroethylamino carbanions
Makosza, Mieczyslaw,Bobryk, Karolina,Krajewski, Dariusz
experimental part, p. 1511 - 1524 (2009/07/17)
Simple and efficient method of synthesis of 2-alkoxycarbonyl, 2-cyano, 2-phenylsulfonyl N-alkylaziridines was elaborated via intramolecular nucleophiles substitution of chloride in 1-N-chloro-2-alkoxycarbonyl (cyano, phenylsulfonyl) ethyl amines. These su
N-(arylthioalkyl)-N'-(aminoalkyl)ureas
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, (2008/06/13)
N-(arylthioalkyl)-N'-(aminoalkyl)ureas and thioureas and oxidation derivatives having the formula STR1 wherein B is thio, sulfinyl or sulfonyl; R1 and R2 are hydrogen, loweralkyl, cycloalkyl, 2-furanyl, phenyl, substituted phenyl or phenyl-loweralkyl and R3 and R4 are hydrogen, loweralkyl, phenyl or phenyl-loweralkyl wherein phenyl is optionally substituted, or R3 and R4 taken with the adjacent nitrogen form a heterocyclic residue.
