4042-61-9 Usage
Description
(4-Acetyl-phenyl)-phosphonic acid, an organophosphorus compound with the chemical formula C8H9O4P, is a phosphonic acid derivative featuring an acetyl group attached to a benzene ring. This versatile chemical serves as a building block in the synthesis of various organic compounds and holds promise as a potential drug intermediate. Its unique structure and properties also make it a candidate for use as a corrosion inhibitor in metals and a catalyst in organic reactions, showcasing its value in organic synthesis and other industrial applications.
Uses
Used in Organic Synthesis:
(4-Acetyl-phenyl)-phosphonic acid is used as a building block for the synthesis of various organic compounds, contributing to the creation of a wide range of chemical products.
Used as a Drug Intermediate:
In the pharmaceutical industry, (4-Acetyl-phenyl)-phosphonic acid serves as a potential drug intermediate, playing a crucial role in the development of new medications.
Used in Corrosion Inhibition:
(4-Acetyl-phenyl)-phosphonic acid has been studied for its potential as a corrosion inhibitor in metals, offering a possible solution to protect metal surfaces from degradation.
Used as a Catalyst in Organic Reactions:
(4-ACETYL-PHENYL)-PHOSPHONIC ACID's unique properties also make it a valuable catalyst in organic reactions, enhancing the efficiency and selectivity of various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 4042-61-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,4 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4042-61:
(6*4)+(5*0)+(4*4)+(3*2)+(2*6)+(1*1)=59
59 % 10 = 9
So 4042-61-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H9O4P/c1-6(9)7-2-4-8(5-3-7)13(10,11)12/h2-5H,1H3,(H2,10,11,12)
4042-61-9Relevant articles and documents
Hydrolysis and alcoholysis of phosphinates and phosphonates
Harsági, Nikoletta,Keglevich, Gy?rgy,Sz?ll?si, Betti,Varga, Petra Regina
, (2021/11/04)
Phosphinic and phosphonic acids useful intermediates and biologically active compounds may be prepared from their esters: phosphinates and phosphonates, respectively, by acid-catalyzed hydrolysis either on conventional heating or on MW irradiation. The transesterification of alkyl phosphinates took place only in the presence of suitable ionic liquids as the catalysts. In the cases of phenylphosphonates, depending on the nature of the ionic liquid, the formation of the ester was accompanied by the fission of the C–O bond.
A robust and simple protocol for the synthesis of arylfluorophosphonates
Leypold, Mario,Wallace, Paal W.,Kljajic, Marko,Schittmayer, Matthias,Pletz, Jakob,Illaszewicz-Trattner, Carina,Guebitz, Georg M.,Birner-Gruenberger, Ruth,Breinbauer, Rolf
, p. 5619 - 5622 (2015/09/21)
Fluorophosphonates represent powerful probes for the identification and analysis of active serine hydrolases in activity based protein profiling. Although alkylphosphonofluoridates are widely used for such purposes, little is known about the synthesis and purification of arylphosphonofluoridates, which may be useful tools for screening enzyme activities toward aromatic esters. Our optimized route makes this subclass of transition state inhibitors broadly accessible for a diverse series of phosphonic acid derivatives using a combination of selective monoesterification with EDC·HCl and subsequent mild fluorination with DAST. All compounds were isolated as pure materials using a simple acid-base extraction protocol in 76-93% yields over two steps. These probes can be stored under an inert atmosphere at -24 °C for several months without significant degradation.
