40423-82-3

Basic information

• Product Name: 2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine
• Synonyms: 2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine
• CAS NO: 40423-82-3
• Molecular Formula: C9H11ClFN3
• Molecular Weight: 216
• Mol File: 40423-82-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 355.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.312±0.06 g/cm3(Predicted)
• PKA: 3.56±0.40(Predicted)
• CAS DataBase Reference: 2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine(40423-82-3)
• EPA Substance Registry System: 2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine(40423-82-3)

Safety Data

• Hazardous Substances Data: 40423-82-3(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 

Relevant articles and documents

SYNTHESIS AND AMINATION OF 2,4-DICHLORO-5-FLUOROPYRIMIDINE

2,4-Dichloro-5-fluoropyrimidine was prepared by the chlorination of 5-fluorouracil with phosphorus pentachloride in absence of solvent.The reaction of 2,4-dichloro-5-pyrimidine with primary and secondary aliphatic and heteroaromatic amines in an aqueous medium yields 2-chloro-4-RR'-amino-5-fluoropyrimidines, with stereoselective substitution of chlorine in the C4 position.The substances obtained have well-defined fungicidal activity.