40424-20-2Relevant academic research and scientific papers
Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2
Ji, Limei,Qu, Lailiang,Wang, Cheng,Peng, Wan,Li, Shang,Yang, Huali,Luo, Heng,Yin, Fucheng,Lu, Dehua,Liu, Xingchen,Kong, Lingyi,Wang, Xiaobing
, (2020/11/12)
Oxidative stress and inflammation are significant risk factors for neurodegenerative disease. The Keap1-Nrf2-ARE pathway is one of the most promising defensive systems against oxidative stress. Here, dozens of piperlongumine analogues were designed, synth
A novel and efficient reaction of imidazolidin-2-one and N-acylbenzotriazoles: A facile synthesis of 1-acylimidazolidin-2-one
Li, Jianjun,Sun, Yan,Chen, Zhiwei,Su, Weike
experimental part, p. 3669 - 3677 (2011/02/23)
Acylation of imidazolidin-2-one with readily available N- acylbenzotriazoles, in the presence of K2CO3, produced 1-acylimidazolidin-2-ones and N,N'-diacyl-imidazolidin-2-one in moderate to good yields. The utilization of N-acylbenzotriazoles which make the reaction simple and mild, may be especially advantageous when the corresponding acid chlorides are not stable or not easily prepared. It's also an example of the reaction of N-acylbenzotriazoles and amide. Copyright
