404353-42-0Relevant academic research and scientific papers
Synthesis and antiplasmodial activity of purine-based C-nucleoside analogues
Singh, Kartikey,Joshi, Prince,Mahar, Rohit,Baranwal, Pragati,Shukla, Sanjeev K.,Tripathi, Renu,Tripathi, Rama Pati
, p. 1232 - 1238 (2018/08/01)
A series of homologous C-nucleoside mimics have been synthesized via an efficient and facile synthetic protocol involving the conjugate addition of purine to sugar derived olefinic ester in good yields. The synthesized compounds were evaluated for their a
Conjugate addition of amines to sugar derived olefinic esters: Synthesis of glycosylated amino esters as DNA topoisomerase-II inhibitors
Khan,Tripathi,Tiwari,Mishra,Reddy,Saxena
, p. 591 - 604 (2007/10/03)
Conjugate addition of amines to olefinic esters derived from sugars leading to formation of glycosylated amino esters in a stereoselective manner is described. Some of the synthesized compounds possess DNA topoisomerase-II enzyme inhibitory activities at low concentrations.
