404356-68-9Relevant academic research and scientific papers
Total synthesis of the furanocembrane bis-deoxylophotoxin
Cases,González-López de Turiso,Pattenden
, p. 1869 - 1872 (2001)
A total synthesis of the bis-deoxylophotoxin 25a, the probable biological precursor to the neurotoxin lophotoxin 1 is described. The synthesis uses a strategy based on sequential carbanion alkylation and Stille coupling between the chiral building blocks
Synthetic studies towards furanocembrane diterpenes. A total synthesis of bis-deoxylophotoxin
Cases, Manuel,De Turiso, Felix Gonzalez-Lopez,Hadjisoteriou, Maria S.,Pattenden, Gerald
, p. 2786 - 2804 (2007/10/03)
Synthetic approaches to the furanocembrane family of natural products, e.g. lophotoxins, pukalides, bipinnatins, based on: i) an intramolecular cyclisation of an α,β-unsaturated acyl radical intermediate into a conjugated enone, viz. 18 → 17, and ii) an i
