404369-25-1

Basic information

• Product Name: 2-Pyrrolidinemethanol, 3-hydroxy-1-(9-phenyl-9H-fluoren-9-yl)-, (2R,3S)-
• CAS NO: 404369-25-1
• Molecular Formula: C24H23NO2
• Molecular Weight: 357.452
• Mol File: 404369-25-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinemethanol, 3-hydroxy-1-(9-phenyl-9H-fluoren-9-yl)-, (2R,3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinemethanol, 3-hydroxy-1-(9-phenyl-9H-fluoren-9-yl)-, (2R,3S)-(404369-25-1)
• EPA Substance Registry System: 2-Pyrrolidinemethanol, 3-hydroxy-1-(9-phenyl-9H-fluoren-9-yl)-, (2R,3S)-(404369-25-1)

Safety Data

• Hazardous Substances Data: 404369-25-1(Hazardous Substances Data)

Upstream product

• 404369-23-9 methyl (2S,3S)-3-(tert-butyldimethylsilyl)oxy-5-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-pentanoate 
• 404369-21-7 methyl (2S,3S)-3-(tert-butyldimethylsilyl)oxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate 
• 404369-19-3 methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-lyxonate 
• 404369-20-6 methyl (2S,3S)-3-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate 
• 214619-42-8 methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-lyxonate 
• 214619-41-7 methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-lyxonate 
• 154494-79-8 methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-mannonate 
• 404369-24-0 trans-3-O-(tert-butyldimethylsilyl)-1-(9-phenyl-9-fluorenyl)-L-proline methyl ester 

Downstream Products

• 105017-31-0 (2R,3S)-2-(hydroxymethyl)-3-hydroxypyrrolidine 

Relevant articles and documents

Efficient synthesis of 3-hydroxyprolines and 3-hydroxyprolinols from sugars

trans-3-Hydroxy-L-proline 1, trans-3-hydroxy-L-prolinol 2, cis-3-hydroxy-D-proline 3, and cis-3-hydroxy-D-prolinol 4 have been prepared in enantiomerically pure form with chirospecific manner. Key intermediates, 2-amino-3-hydroxy-4-pentenoate 9 and 17, were obtained from D-glucono-δ-lactone and L-gulonic acid γ-lactone via a simultaneous dealkoxyhalogenation.