40438-23-1Relevant articles and documents
New Phosphonium Ylides by Functionalization of Triphenylphosphoranylideneacetamide
Wanner, Martin J.,Koomen, Gerrit-Jan
, p. 1513 - 1516 (2007/10/02)
Triphenylphosphoranylideneacetamide undergoes Michael reactions with several acceptors, giving rise, apart from the normal Michael adducts, to the formation of different products like glutarimide ylides and stabilized iminophosphoranes.Wittig reactions with these new ylides lead to a variety of α,β-unsaturated carbonyl compounds. Key Words: Stabilized phosphonium ylides, Wittig reaction, Michael reaction, Glutarimides.
Ester of (triarylphosphoranylidene)carbamic acid having diuretic and ability to lower plasma renin properties
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, (2008/06/13)
Novel triarylphosphinimide derivatives having the formula STR1 wherein R1, R2 and R3 are each at the ortho or meta position, represent mono- or disubstituents and are selected from the group consisting of hydrogen, alkyl(C1 -C3), alkoxy(C1 -C3), trifluoromethyl and halogen; and R4 is selected from the group consisting of alkyl(C1 -C3), alkenyl(C2 -C3), alkynyl(C2 -C4), cycloalkyl(C3 -C5), cycloalkyl(C3 -C6)methyl, 4-oxopentyl, 3-tetrahydrofuranyl, 2,3-dihydro-1H-inden-1-yl, 1-alkyl(C1 -C3)cyclopentyl, trans-2-alkyl(C1 -C3)cyclopentyl, trans-2-alkoxy(C1 -C3)cyclopentyl, 1-cyclopropylethyl, 2-methylcyclopropylmethyl, dicyclopropylmethyl, 2-, 3- or 4-pyridinylmethyl, 2-cyclopenten-1-yl, tetrahydro-2H-pyran-4-yl and cis and trans-2-methoxycyclohexyl; with the proviso that when R4 is alkyl(C1 -C3), R1, R2 and R3 may not each be hydrogen STR2 wherein R1, R2 and R3 are each at the ortho or meta position and are selected from hydrogen and alkyl(C1 -C3), and X is an acid addition salt; processes for producing them, compositions containing them, and methods for using them in mammals to effect diuresis; to lower plasma renin levels and to increase cardiac contractility.
