40440-12-8

Upstream product

• 627-30-5 1-chloro-3-hydroxypropane 

Downstream Products

• 5346-33-8 5-nitro-furfural-[2-(3-hydroxy-propyl)-semicarbazone] 
• 4341-15-5 N-(5-Nitro-2-furfuryliden)-3-amino-3,4,5,6-tetrahydro-1,3-oxazin-2-on 
• 81930-33-8 1-(3-hydroxypropyl)-3,5-dimethyl-1H-pyrazole 
• 84102-05-6 3-Benzyloxymethyl-1,5,6,7-tetrahydro-1-(3-hydroxypropyl)-6-methyl-4H-indazol-4-on 
• 91441-69-9 5-chloro-2-(3-hydroxypropyl)-7,10-bis(phenylmethoxy)anthra[1,9-cd]pyrazol-6(2H)-one 
• 108-59-8 malonic acid dimethyl ester 
• 1176272-74-4 1-(3-hydroxypropyl)-4-(2,4,6-trimethylphenyl)pyrazolidine-3,5-dione 
• 1412895-95-4 C₁₃H₁₄Cl₂N₂O₃ 
• 1221502-38-0 3-[5-(4-fluorophenyl)-3-methyl-1H-pyrazol-1-yl]propan-1-ol 
• 691881-17-1 3-cyclohexyl-1-(3-hydroxypropyl)-4-(4-methylthiophenyl)pyrazol-5-ol 

Relevant academic research and scientific papers

Modulators of STING (Stimulator of Interferon Genes)

Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY

In light of requests to reduce or reverse the wavelength dispersion of the birefringence of a phase-retardation film in order to increase the viewing angle of a liquid crystal display, the present invention provides a polymerizable compound that reduces, for example, the likelihood of crystals precipitating in a polymerizable composition including the polymerizable compound and enables the polymerizable composition to have high preservation stability and a polymerizable composition including the polymerizable compound which reduces the likelihood of inconsistencies being formed in a film-like polymer produced by polymerizing the polymerizable composition. Another object of the present invention is to provide a polymer produced by polymerizing the polymerizable composition and an optically anisotropic body including the polymer.

SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS

The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents the treatment of inflammatory diseases and conditions.

SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS

The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.

POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY

The present invention provides a compound represented by the general formula (I), and a polymerizable composition containing the compound. When the polymerizable composition containing the compound represented by the formula (I) is used to form a filmy product, the resulting filmy product exhibits less change over time in phase difference and reverse wavelength dispersion and when the filmy polymer is irradiated with UV light, peeling from a substrate is unlikely to be caused. Further, the invention provides a polymer obtained through polymerization of the polymerizable composition and an optically anisotropic body obtained using the polymer.

PYRAZOLE COMPOUNDS

The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineralocorticoid receptor antagonistic action and is useful as an agent for the prophylaxis or treatment of a disease or condition mediated by the mineralocorticoid receptor activation.

Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden

Derivatives of the new class of 3-hydroxy-4-phenyl-5-oxo-pyrazolines were optimized towards both herbicidal activity on key annual grass weed species and selectivity in small grain cereal crops. The generic structure can be separated into three parts for the analysis of the structure-activity relationships, namely the aryl, the dione with its prodrug forms and the hydrazine moiety. Each area appears to play distinct and different roles in overall expression of biological performance which is further beneficially influenced by adjuvant response and safener action. Pinoxaden 6, a novel graminicide for use in wheat and barley incorporating a [1,4,5]oxadiazepane ring, eventually emerged as a development candidate from the discovery and optimization process.

Heterocyclic ureas

Ureas of the structure: STR1 WHEREIN X is F or Cl or OCH3 ; Y is O or NH; m is 0, 1 or 2 and N and n' each are 0 or 1 with the proviso that if n' is 1, X is not Cl and if Y is O, X is not Cl are useful in prevention of ozone damage to plants.

Substituted-3-phenyl ureas

Ureas of the structure EQU1 WHEREIN X is F or OCH3 ; Y is O or NH; m is 0, 1 or 2, and n and n' each are 0 or 1, Are useful in prevention of ozone damage to plants.