40441-34-7

Usage

InChI:InChI=1/C8H11BrO/c1-8(2)4-3-7(10)6(9)5-8/h3-4,6H,5H2,1-2H3

Upstream product

• 1073-13-8 4,4-dimethylcyclohexenone 
• 54781-30-5 5,5-dimethyl-2-<(trimethylsilyl)oxy>-1,3-cyclohexadiene 
• 38610-74-1 4,4-dimethylcyclohexa-1,5-dien-1-yl acetate 

Downstream Products

• 1073-14-9 4,4-dimethylcyclohexa-2,5-dienone 
• 137967-04-5 6-(6-bromo-4,4-dimethyl-1-hydroxycyclohex-2-enyl)-4,4-dimethylcyclohex-2-en-1-one 
• 136840-07-8 6--4,4-dimethylcyclohex-2-en-1-one 
• 136840-03-4 2b-Methoxy-1,1-dimethyl-4-oxo-octahydro-3-oxa-cyclopropa[cd]indene-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Cross-conjugated compounds: microwave spectrum of 4,4-dimethyl-2,5-cyclohexadien-1-one

4,4-Dimethyl-2,5-cyclohexadien-1-one has been prepared by a three-step reaction from 4,4-dimethyl-2-cyclohexen-1-one.Microwave transitions of the cross-conjugated compound have been measured over extended regions from 11 to 40 GHz.The spectrum is a classical a-type spectrum of a near-prolate top with many interspersed lines presumably originating from excited vibrational states.No internal rotation splitting could be observed.We were able to assign 108 rotational transitions with J-quantum numbers up to 40.The least-squares fit showed a standard deviation of 30 kHz and yielded the three rotational constants, A = 3332.158(13) MHz, B = 1193.07386(52) MHz, C = 1082.21280(45) MHz, as well as all five quartic centrifugal distortion constants from Watson's A-reduction: ΔJ = 0.02149(73) kHz, ΔJK = 1.1008(16) kHz, ΔK = -68.42(32) kHz, δJ = 0.00332(16) kHz, δK = -2.7513(99) kHz (representation IR used).The dipole moment was determined from the Stark shift of the M-components of two transitions and was found to be 4.4522(83) D from 93 measurements.

Functional Group Hybrids. Reactivity of α'-Nucleofuge α,β-Unsaturated Ketones. 1. Reactions with Organocopper Reagents

A series of α-nucleofuge α',β'-unsaturated ketones encompassing a variety of structural types and nucleofuges was prepared.Treatment of these compounds with lithium dimethylcuprate or methylcopper leads primarily to either reductive cleavage of the α-nucl

5,5-Dibromobarbituric Acid, a Convenient New Reagent for the Bromination of Saturated and α,β-Unsaturated Carbonyl Compounds

5,5-Dibromobarbituric acid (1) was used for the bromination of saturated and α,β-unsaturated aldehydes and keto compounds.

Anti-androgen compounds

Compounds of the formula STR1 in which each R is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, hydroxy, cyano, or halo, and both R groups are identical and are symmetrically located; R 1 is C 1 -C 3 alkyl and R 2 is methyl, or R 1 and R 2 taken together are (CH 2 -- n in which n is an integer from 4 to 6; and (1) X c and X d are hydrogen, and the combination of X a and Y a and of X b and Y b each represents a double bond, subject to the limitation that, when R 1 is C 1 -C 3 alkyl and is other than methyl, X c, X d, and R 1 are all in an α-configuration; or (2) X a, X b, X c, X d, Y a, and Y b are hydrogen, subject to the limitation that both X c and X d are in an α-configuration, both X a and X b are in an α-configuration or in a β-configuration, and, R 1, when it is C 1 -C 3 alkyl, is in an α-configuration, are useful in inhibiting the action of androgens or are intermediates to such anti-androgen compounds.