404574-43-2

Upstream product

• 915-35-5 hecogenin acetate 
• 227178-66-7 3β-acetoxy-12β-hydroxy-5α-spirostan-14-ene 
• 6917-04-0 (25R)-3β-Acetoxy-12,13-seco-5α-spirost-13-en-12-on 
• 78179-61-0 3β-acetoxy-12-keto-5α-spirostan-14-ene 
• 78179-60-9 3β-acetoxy-12α-hydroxy-5α-spirostan-14-ene 

Downstream Products

• 868162-83-8 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-17-((S)-1,5-dimethyl-2-oxo-hex-5-enyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 
• 868162-81-6 3β-acetoxy-12b-benzoyloxy-22-hydroxy-5α-furostan-14,16-diene 
• 868162-65-6 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-10,13-dimethyl-17-{(S)-1-[2-(3-methyl-but-3-enyl)-[1,3]dioxan-2-yl]-ethyl}-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 
• 868162-85-0 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-17-{(S)-1-[5,5-dimethyl-2-(3-methyl-but-3-enyl)-[1,3]dioxan-2-yl]-ethyl}-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 
• 868162-84-9 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-17-{(S)-1-[5,5-dibromo-2-(3-methyl-but-3-enyl)-[1,3]dioxan-2-yl]-ethyl}-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 
• 868162-88-3 C₄₁H₅₆O₈ 
• 868162-82-7 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-17-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hex-5-enyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 

Relevant academic research and scientific papers

Transetherification-mediated E-ring opening and stereoselective "red-Ox" modification of furostan

We have developed a novel E-ring opening method for furostan, and applied it to prepare D-ring modified steroids, which can be used to synthesize cephalostatin analogs.

Synthesis of 14′,15′-dehydro-ritterazine y via reductive and oxidative functionalizations of hecogenin acetate

An analog of ritterazine Y was synthesized from hecogenin acetate in 23 steps via functional group manipulations of hecogenin acetate. Preparation of the north G and south Y units and the late stage Guo-Fuchs asymmetric coupling of the both units afforded

A biomimetically inspired, efficient synthesis of the south 7 hemisphere of cephalostatin 7

Synthesis of the South 7 hemisphere of cephalostatin 7 is described applying a second-generation synthetic strategy, which retains all the existing carbons in hecogenin acetate 1. TFAT (trifluoroacetyl trifluoromethanesulfonate)-assisted E-ring opening yi