404594-16-7

Usage

Uses

Used in Pharmaceutical Industry:
1-BOC-3-(METHYLAMINOMETHYL)-PYRROLIDINE is used as a synthetic intermediate for the development of new pharmaceutical compounds due to its ability to be incorporated into complex molecular structures, enhancing the biological activity and therapeutic potential of the final products.
Used in Agrochemical Industry:
1-BOC-3-(METHYLAMINOMETHYL)-PYRROLIDINE is used as a precursor in the synthesis of agrochemicals, contributing to the creation of new pesticides or other agricultural chemicals that can improve crop protection and yield.
Used in Organic Synthesis:
1-BOC-3-(METHYLAMINOMETHYL)-PYRROLIDINE is used as a versatile building block in organic synthesis for the preparation of a wide range of organic compounds, taking advantage of its functional groups to facilitate various chemical reactions and the formation of diverse molecular structures.

Upstream product

• 72925-16-7 1-boc-pyrrolidine-3-carboxylic acid 
• 74-89-5 methylamine 
• 59379-02-1 tert-butyl 3-formylpyrrolidine-1-carboxylate 
• 199174-24-8 tert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 274692-06-7 tert-butyl (S)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

OXOPYRIDO[1,2-A]PYRIMIDINE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION

The present invention relates to novel compounds of formula (I), wherein R1 to R7 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

NOVEL COMPOUNDS

The present invention relates to substituted 5-membered nitrogen containing heteroaryl compounds, such as sulfonyl triazoles, where the heteroaryl ring is further substituted, optionally via a linking group such as -NH-, with a cyclic group which in turn is substituted at the α-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

Novel Compounds

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C- terminal hydrolase 30 or Ubiquitin Specific Peptidase 30 (USP30). The invention further relates to the use of DUB inhibitors in the treatment of conditions involving mitochondrial dysfunction and cancer. Compounds of the invention include compounds having the formula (I): (I) or a pharmaceutically acceptable salt thereof, wherein R1a, R1b, R1c, R1d, R1e, R1f, R1g, R2, X, L and A are as defined herein.

Synthesis and antibacterial activity of novel 1 β-methyl carbapenems with cycloalkylamine moiety at the C-2 position

Novel 1β-methyl carbapenems with a cycloalkylamine moiety as a side chain were synthesized and their structure-activity relationships were studied. These carbapenems showed potent antibacterial activities against a wide range of range of Gram-positive and Gram-negative bacteria, and moderate urinary recovery when administered intraperitoneally in mice.