404594-20-3Relevant academic research and scientific papers
Synthesis and antibacterial activity of novel 1 β-methyl carbapenems with cycloalkylamine moiety at the C-2 position
Kawamoto, Isao,Shimoji, Yasuo,Kanno, Osamu,Endo, Rokuro,Miyauchi, Masau,Kojima, Katsuhiko,Ishikawa, Katsuya,Morimoto, Munetsugu,Ohya, Satoshi
, p. 1080 - 1092 (2007/10/03)
Novel 1β-methyl carbapenems with a cycloalkylamine moiety as a side chain were synthesized and their structure-activity relationships were studied. These carbapenems showed potent antibacterial activities against a wide range of range of Gram-positive and Gram-negative bacteria, and moderate urinary recovery when administered intraperitoneally in mice.
