274692-07-8

Usage

Uses

Used in Pharmaceutical Applications:
(R)-3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a pharmacophore for [application reason], due to its potential to contribute to the activity of a drug.
Used in Chemical Reactions:
(R)-3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a reactant or intermediate in [application reason], given its specific isomer characteristics and functional groups that can participate in various chemical transformations.
Used in Synthetic Chemistry:
(R)-3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a building block in the synthesis of more complex molecules for [application reason], taking advantage of its structural features and reactivity in chemical reactions.

Upstream product

• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 274692-06-7 tert-butyl (S)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate 
• 138108-72-2 tert-butyl (R)-3-hydroxymethylpyrrolidine-1-carboxylate 
• 773837-37-9 sodium cyanide 
• 1391730-27-0 tert-butyl (S)-3-(4-methylbenzenesulfonyloxymethyl)pyrrolidine-1-carboxylate 
• 199174-24-8 tert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 274692-08-9 tert-butyl (3S)-3-(2-aminoethyl)pyrrolidine-1-carboxylate 
• 890849-28-2 (R)-tert-butyl 3-(2-oxoethyl)pyrrolidine-1-carboxylate 
• 404594-20-3 (S)-1-tert-butoxycarbonyl-3-(benzyloxycarbonylaminoethyl)pyrrolidine 
• 404594-23-6 (S)-1-tert-butoxycarbonyl-3-[N-methyl-N-(benzyloxycarbonyl)aminoethyl]pyrrolidine 

Relevant academic research and scientific papers

FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

METHODS OF TREATING LIVER DISEASES

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e.g., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.

Synthesis and antibacterial activity of novel 1 β-methyl carbapenems with cycloalkylamine moiety at the C-2 position

Novel 1β-methyl carbapenems with a cycloalkylamine moiety as a side chain were synthesized and their structure-activity relationships were studied. These carbapenems showed potent antibacterial activities against a wide range of range of Gram-positive and Gram-negative bacteria, and moderate urinary recovery when administered intraperitoneally in mice.