40460-69-3

Upstream product

• 40460-91-1 2-(4-bromophenyl)propanal 
• 100-46-9 benzylamine 

Downstream Products

• 1233867-67-8 4-(4-bromophenyl)-5-butyl-4-methyl-2-cyclohexen-1-one 
• 1233867-63-4 4-(4-bromophenyl)-4,5-dimethyl-2-cyclohexen-1-one 

Relevant academic research and scientific papers

Proline sulphonamide-catalysed Yamada-Otani condensation: Reaction development, substrate scope and scaffold reactivity

The development of a proline sulphonamide-catalysed method for enantioselective and diastereoselective construction of functionalized cyclohexenones is described. Impact of catalyst structure as well as solvent effects and additives are explored. A significant substrate scope is demonstrated by variation of both the aldehyde and the enone components. Diastereoselective derivatization of the cyclohexenone scaffold illustrates its utility as a building block for chemical synthesis.