404827-81-2

Upstream product

• 45743-05-3 2-chlorobenzimidamide 
• 873-32-5 2-Chlorobenzonitrile 
• 1059172-57-4 2-(2-chlorophenyl)-5,6-dimethylpyrimidin-4-ol 

Downstream Products

• 544678-50-4 6-{2-[2-(2-Chloro-phenyl)-5,6-dimethyl-pyrimidin-4-ylamino]-ethylamino}-nicotinonitrile 
• 1059172-55-2 N-(2-(2-chlorophenyl)-5,6-dimethylpyrimidin-4-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine 

Relevant academic research and scientific papers

AMINOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

PYRIMIDINES AND PYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful as inhibitors of protein kinases, such as inhibitors of GSK-3. The invention provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. The invention provides processes for preparing compounds of the invention. The invention provides methods of identifying compounds useful for treatment of diabetes, diabetic neuropathy, osteoporosis, Alzheimer's disease, Huntington's disease, Parkinson's disease, AIDS-associated dementia, bipolar disorder, amyotrophic lateral sclerosis, multiple sclerosis, schizophrenia, leukocytopenia, cardiomyocyte hypertrophy, stroke, post-stroke, spinal cord injury, traumatic brain injury, Charcot-Marie-Tooth, peripheral nerve regeneration, and rheumatoid arthritis.