45743-05-3

Usage

Uses

2-Chloro-benzamidine, HCl

InChI:InChI=1/C7H7ClN2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H3,9,10)

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 56935-60-5 2-chloro-benzamide oxime 

Downstream Products

• 108444-60-6 2-(2-Chloro-phenyl)-5-vinyl-pyrimidine 
• 670-83-7 2,4-diphenyl-1H-imidazole 
• 83217-16-7 4,6-dichloro-2-(2-chlorophenyl)-pyrimidine 
• 1171113-79-3 2-[2-(2-chlorophenyl)-1H-imidazol-4-yl]-5-phenyloxazole 
• 609-66-5 2-chlorobenzamide 
• 23031-78-9 3-aminobenzisothiazole 
• 14225-76-4 6-methyl-2-(2-chlorophenyl)benzimidazole 
• 14225-75-3 6-chloro-2-(2-chlorophenyl)benzimidazole 
• 1059172-55-2 N-(2-(2-chlorophenyl)-5,6-dimethylpyrimidin-4-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine 
• 404827-81-2 4-chloro-2-(2-chloro-phenyl)-5,6-dimethyl-pyrimidine 
• 1229380-49-7 C₇H₆BrClN₂ 
• 1059172-57-4 2-(2-chlorophenyl)-5,6-dimethylpyrimidin-4-ol 
• 1025029-62-2 tert-butyl 3-(2-(2-chlorophenyl)-6-hydroxy-pyrimidin-4-yl)-azetidine-1-carboxylate 
• 1025029-46-2 2-(2-chloro-phenyl)-pyrimidine-4,6-diol 

Relevant academic research and scientific papers

INHINITORS OF GLI1 AS THERAPEUTIC AGENTS

This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to glioma- associated oncogene (Gli) expression. More particularly, this disclosure relate

AMINOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS

The present invention is directed to novel compounds of formula (I) and their use in treating metabolic diseases.

PYRIMIDINES AND PYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful as inhibitors of protein kinases, such as inhibitors of GSK-3. The invention provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. The invention provides processes for preparing compounds of the invention. The invention provides methods of identifying compounds useful for treatment of diabetes, diabetic neuropathy, osteoporosis, Alzheimer's disease, Huntington's disease, Parkinson's disease, AIDS-associated dementia, bipolar disorder, amyotrophic lateral sclerosis, multiple sclerosis, schizophrenia, leukocytopenia, cardiomyocyte hypertrophy, stroke, post-stroke, spinal cord injury, traumatic brain injury, Charcot-Marie-Tooth, peripheral nerve regeneration, and rheumatoid arthritis.

INHIBITORS OF HCV NS5B POLYMERASE

The present invention porivdes compounds of Formula I, compositons and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.

5-acylamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them

The invention relates to thiadiazole derivatives corresponding to the general formula STR1 in which Ar represents a nitrogen-containing aromatic heterocycle, in particular indolyl which is substituted or unsubstituted on the nitrogen atom with CO--(C