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6-BROMO-2-(2-METHYLPHENYL)-4H-3,1-BENZOXAZIN-4-ONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

404835-95-6

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404835-95-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 404835-95-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,4,8,3 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 404835-95:
(8*4)+(7*0)+(6*4)+(5*8)+(4*3)+(3*5)+(2*9)+(1*5)=146
146 % 10 = 6
So 404835-95-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H10BrNO2/c1-9-4-2-3-5-11(9)14-17-13-7-6-10(16)8-12(13)15(18)19-14/h2-8H,1H3

404835-95-6Relevant academic research and scientific papers

QUINAZOLINONE DERIVATIVES USEFUL FOR IMAGING

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Paragraph 0172, (2020/02/14)

Compounds comprising quinazolinone derivatives and methods of identification and use of imaging agents. The compounds have the general formula I: wherein R2 is selected from halogen, halosubstituted alkyl, alkyl, hydroxyl-alkyl, and amino-alkyl; X is sele

Development of Candidates for Positron Emission Tomography (PET) Imaging of Ghrelin Receptor in Disease: Design, Synthesis, and Evaluation of Fluorine-Bearing Quinazolinone Derivatives

Hou, Jinqiang,Kovacs, Michael S.,Dhanvantari, Savita,Luyt, Leonard G.

, p. 1261 - 1275 (2018/02/17)

Molecular imaging with positron emission tomography (PET) is an attractive platform for noninvasive detection and assessment of disease. The development of a PET imaging agent targeting the ghrelin receptor (growth hormone secretagogue receptor type 1a or

Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity

Rudolph, Joachim,Esler, William P.,O'Connor, Stephen,Coish, Philip D. G.,Wickens, Philip L.,Brands, Michael,Bierer, Donald E.,Bloomquist, Brian T.,Bondar, Georgiy,Chen, Libing,Chuang, Chih-Yuan,Claus, Thomas H.,Fathi, Zahra,Fu, Wenlang,Khire, Uday R.,Kristie, James A.,Liu, Xiao-Gao,Lowe, Derek B.,McClure, Andrea C.,Michels, Martin,Ortiz, Astrid A.,Ramsden, Philip D.,Schoenleber, Robert W.,Shelekhin, Tatiana E.,Vakalopoulos, Alexandras,Tang, Weifeng,Wang, Lei,Yi, Lin,Gardell, Stephen J.,Livingston, James N.,Sweet, Laurel J.,Bullock, William H.

, p. 5202 - 5216 (2008/03/12)

The peptide hormone ghrelin is the endogenous ligand for the type 1a growth hormone secretagogue receptor (GHS-R1a) and the only currently known circulating appetite stimulant. GHS-R1a antagonism has therefore been proposed as a potential approach for obe

QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE

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Page/Page column 39, (2010/10/19)

This invention relates to substituted quinazolinone derivatives, compositions, and methods for treating diabetes, obesity and related disorders, and regulation of food intake (e.g., stimulation and suppression).

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