404887-62-3

Upstream product

• 50609-85-3 (E)-3-methylamino-3-methylthio-1-phenylprop-2-ene-1-thione 
• 742088-27-3 [5α-cholest-2-en-3-yloxy]trimethylsilane 

Relevant academic research and scientific papers

Reactions of thiobenzoylketene S,N-acetals with silyl enol ethers of cyclic ketones in the presence of desilylating reagents: formation and desulfurization of thienolactams

Medium-sized thienolactams can be directly prepared from thiobenzoylketene S,N-acetals, Hg(OAc)2, and silyl enol ethers of cyclic ketones, and either TBAF or TASF. However, by adding either water or alcohol to the foregoing mixture, 3-methylamino-5-phenylthiophenes, in which the ω-position of long-chain alkanoic acids and alkanoic esters are bonded to C-2 of the thiophene ring, can be obtained albeit in low yields. Sequential treatment of the thienolactams with Raney nickel and Adam's catalyst result in completely reductive desulfurization of thienolactams molecules.