404922-80-1 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 9 carbon (C), 7 hydrogen (H), 1 bromine (Br), 1 chlorine (Cl), and 3 nitrogen (N) atoms.
Explanation
The compound is a derivative of 1H-1,2,4-triazole, which is a five-membered heterocyclic ring containing three nitrogen atoms and two carbon atoms. It has a substituted phenyl ring (a six-membered carbon ring with alternating single and double bonds) attached to it.
Explanation
The compound contains a bromomethyl (-CH2Br) group and a chlorophenyl (-C6H4Cl) group, which are attached to the phenyl ring. These substituents can influence the compound's reactivity and biological activity.
Explanation
Triazoles, in general, have a wide range of pharmacological activities, such as antifungal, antibacterial, and anticancer properties. This specific compound, due to its unique structure and substituents, may have potential applications in the development of new drugs.
Explanation
The compound's triazole core and its substituents may contribute to its potential pharmacological activities, which include fighting fungal infections, bacterial infections, and cancer cells.
Explanation
Due to its unique structure and potential pharmacological activities, 1H-1,2,4-Triazole, 1-[2-(bromomethyl)-4-chlorophenyl]is an important target for further research and development in the field of pharmaceutical chemistry. This may lead to the discovery of new drugs with improved efficacy and safety profiles.
Chemical structure
1H-1,2,4-Triazole derivative with a substituted phenyl ring
Substituents
Bromomethyl and chlorophenyl groups
Potential applications
Medicinal chemistry and drug development
Pharmacological activities
Antifungal, antibacterial, and anticancer properties
Importance in pharmaceutical chemistry
Target for further research and development
Check Digit Verification of cas no
The CAS Registry Mumber 404922-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,4,9,2 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 404922-80:
(8*4)+(7*0)+(6*4)+(5*9)+(4*2)+(3*2)+(2*8)+(1*0)=131
131 % 10 = 1
So 404922-80-1 is a valid CAS Registry Number.
404922-80-1Relevant academic research and scientific papers
Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization
Deng, James Z.,McMasters, Daniel R.,Rabbat, Philippe M.A.,Williams, Peter D.,Coburn, Craig A.,Yan, Youwei,Kuo, Lawrence C.,Lewis, S. Dale,Lucas, Bobby J.,Krueger, Julie A.,Strulovici, Berta,Vacca, Joseph P.,Lyle, Terry A.,Burgey, Christopher S.
, p. 4411 - 4416 (2007/10/03)
Thrombin-inhibitor X-ray crystal structures, in combination with the installation of binding elements optimized within the pyrazinone series of thrombin inhibitors, were utilized to transform a weak triazolopyrimidine lead into a series of potent oxazolop
Thrombin inhibitors
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Page 21, (2008/06/13)
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof.
