40504-79-8Relevant academic research and scientific papers
Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution
Xiao, Kai-Jiong,Chu, Ling,Yu, Jin-Quan
supporting information, p. 2856 - 2860 (2016/02/27)
Significant progress has been made in the past decade regarding the development of enantioselective C-H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C-H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C-H activation and C-C bond formation, thus significantly expanding the scope of enantioselective C-H activation reactions.
Reaction of fluorine-containing organomagnesium compounds with diethyl esters of dicarboxylic acids
Dormidontov, Yu. P.,Shadrina, L. P.,Belogai, V. D.,Krokhalev, A. M.,Yakhlakova, O. M.
, p. 92 - 95 (2007/10/02)
The reaction of arylmagnesium halides containing fluorine atoms in the ring or sidechain with the esters of dicarboxylic acids gives esters of hydroxyacids or oxoacids depending on the residue of the organomagnesium compounds and pKa (1) value of the acid related to the ester involved in the reaction.
