405090-09-7

Usage

General Description

1-Pyrrolidinecarboxylic acid, 3-[[(methylsulfonyl)oxy]methyl]-, phenylmethyl ester, (3R)- is a chemical compound with the molecular formula C20H25NO4S. It is a derivative of pyrrolidinecarboxylic acid, and the (3R)- designation indicates the stereochemistry of the compound. The presence of the phenylmethyl ester group suggests that 1-Pyrrolidinecarboxylic acid, 3-[[(methylsulfonyl)oxy]methyl]-, phenylmethyl ester, (3R)- may have applications in organic synthesis and pharmaceutical chemistry. The (methylsulfonyl)oxy)methyl group indicates the presence of a sulfonyl group, which can have diverse chemical properties and may be relevant to the compound's reactivity and potential uses. Overall, 1-Pyrrolidinecarboxylic acid, 3-[[(methylsulfonyl)oxy]methyl]-, phenylmethyl ester, (3R)- is likely of interest to researchers and industries working in the fields of organic chemistry, drug discovery, and medicinal chemistry.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 192214-05-4 benzyl (R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

Novel pyrido[2,3-b]indole compounds for the treatment and prophylaxis of bacterial infection

The present invention relates to novel compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

A urea-biphenyl compound and its composition and use thereof

The invention relates to biphenyl derivatives as well as a preparation method and a pharmaceutical composition and application thereof on medicines. And particularly, the invention relates to novel urea-substituted biphenyl derivatives as well as a pharma

Method of treating addiction or dependence using a ligand for a monoamine receptor or transporter

One aspect of the present invention relates to a method of treating of drug addiction or drug dependence in a mammal, comprising the step of administering to a mammal in need thereof a therapuetically effective amount of a heterocyclic compound, e.g., a 3-substituted piperidine. In a preferred embodiment, the method of the present invention treats cocaine addiction or methamphetamine addiction.

Ligands for monoamine receptors and transporters, and methods of use thereof

One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.