405198-79-0Relevant articles and documents
Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions
Yu, Shu-Yan,Gao, Li-Hong,Wu, Jing-Xin,Lan, Hong-Bing,Ma, Yi,Yin, Zhi-Gang
, p. 3303 - 3310 (2020/04/27)
An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramolecular hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed. This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.
Fused-Ring Formation by an Intramolecular “Cut-and-Sew” Reaction between Cyclobutanones and Alkynes
Deng, Lin,Jin, Likun,Dong, Guangbin
supporting information, p. 2702 - 2706 (2018/02/12)
The development of a catalytic intramolecular “cut-and-sew” transformation between cyclobutanones and alkynes to construct cyclohexenone-fused rings is described herein. The challenge arises from the need for selective coupling at the more sterically hind
Efficient synthesis of isothiochromene derivatives by Pd-catalyzed hydrothiolation reaction
Feng, Jie,Lv, Meifang,Lu, Guoping,Cai, Chun
supporting information, p. 5312 - 5317 (2014/10/15)
An efficient method for the preparation of isothiochromene derivatives through the palladium-catalyzed intramolecular hydrothiolation reaction of halides and thiourea is reported. Two carbon-sulfur bonds are formed in this one-pot palladium-catalyzed cascade reaction. This new protocol is free from foul-smelling thiols and operates under mild conditions to give isothiochromene derivatives in excellent yields and with excellent 6-endo-dig selectivity. Copyright
