40534-33-6

Usage

Uses

Used in Pharmaceutical Industry:
1-(1-Methyl-1H-pyrazol-4-yl)ethanol is used as a solvent and intermediate for the production of pharmaceuticals, facilitating the synthesis of various medicinal compounds due to its ability to dissolve a wide range of substances and participate in chemical reactions.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(1-Methyl-1H-pyrazol-4-yl)ethanol is utilized as a component in the formulation of herbicides, contributing to the development of effective weed control agents that are crucial for agricultural productivity.
Used in Corrosion Inhibition:
1-(1-Methyl-1H-pyrazol-4-yl)ethanol is employed as a corrosion inhibitor, protecting metal surfaces from degradation in various industrial applications, thereby extending the lifespan of equipment and infrastructure.
Used in Surfactant Synthesis:
As a key component in the synthesis of surfactants, 1-(1-Methyl-1H-pyrazol-4-yl)ethanol is used to create compounds that lower the surface tension of liquids, which is vital in a multitude of industrial and consumer products for improved performance and efficiency.
Used in Ethyleneamine Production:
1-(1-Methyl-1H-pyrazol-4-yl)ethanol serves as a precursor for the production of ethyleneamines, which are essential in the manufacturing of detergents, textile additives, and fuel additives, enhancing the performance of these products in their respective applications.
Used in Personal Care Industry:
In the personal care sector, 1-(1-Methyl-1H-pyrazol-4-yl)ethanol is used in the manufacturing of products such as shampoos, hair conditioners, and soaps, where it contributes to the formulation of mild and effective cleansing agents.
Overall, 1-(1-Methyl-1H-pyrazol-4-yl)ethanol's diverse applications highlight its importance in the production of numerous consumer and industrial products, making it a valuable compound in today's chemical industry.

InChI:InChI=1/C6H10N2O/c1-5(9)6-3-7-8(2)4-6/h3-5,9H,1-2H3

Upstream product

• 25016-11-9 1-methylpyrazole-4-carbaldehyde 
• 75-16-1 methylmagnesium bromide 
• 37687-18-6 1-(1-methyl-1H-pyrazol-4-yl)-1-ethanone 

Downstream Products

• 37687-18-6 1-(1-methyl-1H-pyrazol-4-yl)-1-ethanone 

Relevant academic research and scientific papers

Discovery, design, and synthesis of indole-based EZH2 inhibitors

The discovery and optimization of a series of small molecule EZH2 inhibitors is described. Starting from dimethylpyridone HTS hit (2), a series of indole-based EZH2 inhibitors were identified. Biochemical potency and microsomal stability were optimized during these studies and afforded compound 22. This compound demonstrates nanomolar levels of biochemical potency (IC50 = 0.002 μM), cellular potency (EC50 = 0.080 μM), and afforded tumor regression when dosed (200 mpk SC BID) in an EZH2 dependent tumor xenograft model.

PYRAZOLE DERIVATIVES

A compound represented by formula (I): (wherein Ar1 represents a phenyl group which may have 1 to 3 substituents, or a non-substituted 5- or 6-membered aromatic heterocyclic group; Ar2 represents (i) a non-substituted phenyl group, (ii) a phenyl group which has been substituted by a lower alkyl group having 1 to 3 groups or atoms selected from among a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom, or (iii) a 5- or 6-membered nitrogen-containing aromatic heterocyclic group which has been substituted by 1 to 3 groups or atoms selected from among a lower alkyl group, a lower alkynyl group, a lower alkanoyl group, a carbamoyl group, a cyano group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom; and X represents a group represented by formula (II): (wherein the ring structure represents a 4- to 7-membered heterocyclic group which may have, in addition to the nitrogen atom shown in formula (II), one heteroatom selected from among nitrogen, oxygen, and sulfur, and which may be substituted by 1 to 4 groups or atoms selected from among a lower alkyl group, a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, an oxo group, a lower alkanoyl group, a lower alkylsulfonyl group, and a halogen atom)), a salt thereof, a solvate of the compound or the salt, and a drug.

PYRAZOLE DERIVATIVE

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.