405505-92-2

Basic information

• Product Name: (2R,4R)-5-tret-butyldiphenylsilyoxy-2-ethyl-4-methylpentanal
• Synonyms: (2R,4R)-5-tret-butyldiphenylsilyoxy-2-ethyl-4-methylpentanal
• CAS NO: 405505-92-2
• Molecular Weight: 382.618
• Mol File: 405505-92-2.mol

Chemical Properties

• CAS DataBase Reference: (2R,4R)-5-tret-butyldiphenylsilyoxy-2-ethyl-4-methylpentanal(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-5-tret-butyldiphenylsilyoxy-2-ethyl-4-methylpentanal(405505-92-2)
• EPA Substance Registry System: (2R,4R)-5-tret-butyldiphenylsilyoxy-2-ethyl-4-methylpentanal(405505-92-2)

Safety Data

• Hazardous Substances Data: 405505-92-2(Hazardous Substances Data)

Upstream product

• 405506-12-9 (2R,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-2-ethyl-4-methyl-pentanoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 72297-78-0 (2S)-(tert-butyl)(3-iodo-2-methylpropoxy)diphenylsilane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 
• 95514-04-8 (R)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 405506-13-0 (2R,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-2-ethyl-4-methyl-pentan-1-ol 

Relevant articles and documents

Synthetic studies toward bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus

(formula presented) The total synthesis of two stereoisomers of a bioactive cyclic peroxide isolated from the marine sponge Plakortis angulospiculatus has been achieved in 18 steps with an overall yield of 2.8%. Diels-Alder addition of singlet oxygen to an acyclic triene carboxylic acid precursor was used to construct the 3,6-dihydro-1,2-dioxin ring. By comparing spectral data of the synthesized compounds and the natural material, we tentatively assign the absolute stereochemistry for the natural product as 3S,6R,8S,10R.