405506-89-0Relevant academic research and scientific papers
Stable Bromiranium Ions with Weakly-Coordinating Counterions as Efficient Electrophilic Brominating Agents
Ascheberg, Christoph,Bock, Jonathan,Bu?, Florenz,Mück-Lichtenfeld, Christian,Daniliuc, Constantin G.,Bergander, Klaus,Dielmann, Fabian,Hennecke, Ulrich
, p. 11578 - 11586 (2017)
Electrophilic halogenating agents are an important class of reagents in chemical synthesis. Herein, we show that sterically demanding bromiranium ions with weakly coordinating counterions are highly reactive electrophilic brominating agents. Despite their
Regioselective palladium-catalyzed alkylation of allylic halides with benzylic Grignard reagents. Two-step synthesis of abietane terpenes and tetracyclic polyprenoid compounds
Rosales, Viale,Zambrano, Jorge L.,Demuth, Martin
, p. 1167 - 1170 (2007/10/03)
A highly regioselective palladium-catalyzed α-alkylation of allylic bromides 1a,c-e and chloride 1b with substituted and unsubstituted benzylic Grignard reagents is reported. The resulting alltrans polyenehomobenzene derivatives were obtained in excellent yields and regioselectivity. These products were easily converted to abietane-type diterpenes (10-12) and tetracyclic polyprenoid compounds (13, 14) through a Lewis acid-promoted cascade polyene cyclization reaction.
