40570-26-1Relevant academic research and scientific papers
(3+3)-Annulation of Carbonyl Ylides with Donor–Acceptor Cyclopropanes: Synergistic Dirhodium(II) and Lewis Acid Catalysis
Petzold, Martin,Jones, Peter G.,Werz, Daniel B.
supporting information, p. 6225 - 6229 (2019/03/21)
The first (3+3)-annulation process of donor–acceptor cyclopropanes using synergistic catalysis is reported. The Rh2(OAc)4-catalyzed decomposition of diazo carbonyl compounds generated carbonyl ylides in situ. These 1,3-dipoles were c
Synthesis of indolin-2-one, isoindolin-1-one, and indole derivatives from homophthalic acid
Kilikli, Alper A.,Dengiz, Cagatay,Oezcan, Sevil,Balci, Metin
experimental part, p. 3697 - 3705 (2011/12/21)
We hereby report the preparation of indolin-2-one and isoindolin-1-one and their derivatives starting from 2-(carboxymethyl)benzoic acid, which was first regiospecifically converted into the isomeric half esters. Transformation of the acid functionalities to the acyl azides followed by Curtius rearrangement gave the regioisomeric isocyanates. Reaction of the isocyanates with aniline produced urethane derivatives. Intramolecular cyclization provided the target compounds. Georg Thieme Verlag Stuttgart. New York.
