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405887-43-6

405887-43-6

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405887-43-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 405887-43-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,5,8,8 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 405887-43:
(8*4)+(7*0)+(6*5)+(5*8)+(4*8)+(3*7)+(2*4)+(1*3)=166
166 % 10 = 6
So 405887-43-6 is a valid CAS Registry Number.

405887-43-6Downstream Products

405887-43-6Relevant articles and documents

Cinnamylindoline derivatives: Synthesis and factor Xa (FXa) inhibitory activities

Noguchi, Tetsuji,Tanaka, Naoki,Nishimata, Toyoki,Goto, Riki,Hayakawa, Miho,Sugidachi, Atsuhiro,Ogawa, Taketoshi,Asai, Fumitoshi,Fujimoto, Koichi

, p. 1494 - 1504 (2008/12/23)

A series of cinnamylindoline derivatives were synthesized, and their factor Xa (FXa) inhibitory activities and selectivity over trypsin were evaluated. Among them, some novel derivatives showed potent FXa inhibitory activities and good selectivity over trypsin. Especially, (E)-2-{5-[1-(acetimidoyl)piperidin-4- yloxy]-2-[2-(5-amidino-2-hydroxyphenyl)ethen-1-yl]indolin-1-ylsulfonyl}acetic acid (22f) having 2-hydroxycinnamyl moiety exhibited the most potent FXa inhibitory activity in vitro. Furthermore, 22f also exhibited potent anticoagulant activities in vitro.

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