406174-97-8

Upstream product

• 406174-96-7 N-(6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-N-methoxymethyl-4-methyl-benzenesulfonamide 
• 406174-94-5 (1R,2S)-6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 406174-93-4 6,7-dimethoxy-3,4-dihydro-naphthalene-2-carboxylic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester 
• 406174-95-6 N-((1R,2R)-6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-4-methyl-benzenesulfonamide 
• 406174-91-2 (1R,2R)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylamine 
• 406174-92-3 (1R,2R)-6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid 

Downstream Products

• 174691-84-0 dihydrexidine 

Relevant academic research and scientific papers

The first asymmetric synthesis of a dopamine D1 agonist, dihydrexidine, employing asymmetric conjugate addition technology

The first asymmetric synthesis of benzophenanthridine dopamine D1 full agonist, dihydrexidine, was accomplished employing three key processes, external chiral ligand-controlled conjugate addition of phenyllithium, Curtius conversion of a carboxylic group