406232-79-9

Usage

Uses

Used in Organic Synthesis:
5-Bromo-2-chloro(trifluoromethoxy)benzene is used as a building block in the synthesis of various organic compounds. Its high chemical reactivity allows for the formation of new chemical bonds and the creation of a wide range of organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-Bromo-2-chloro(trifluoromethoxy)benzene is utilized as a key intermediate in the development of new drugs. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceutical compounds with potential therapeutic applications.
Safety Precautions:
Due to its potential health hazards, 5-Bromo-2-chloro(trifluoromethoxy)benzene should be handled with care and only by trained professionals in a laboratory setting. Proper safety measures, such as wearing protective gear and working in a well-ventilated area, should be taken to minimize risks associated with its use.

InChI:InChI=1/C7H3BrClF3O/c8-4-1-2-5(9)6(3-4)13-7(10,11)12/h1-3H

Upstream product

• 175278-09-8 4-bromo-2-(trifluoromethoxy)aniline 
• 7447-39-4 copper(II) chloride 
• 1535-75-7 2-trifluoromethoxy aniline 

Downstream Products

• 902757-07-7 4-chloro-3-(trifluoromethoxy)phenylboronic acid 

Relevant academic research and scientific papers

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), Wherein X1 , R1 , R2 , R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

INDOLES USEFUL IN THE TREATMENT OF INFLAMATION

There is provided compounds of formula (I), Wherein T, Y, X1 , R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

N-acylsulfonamide apoptosis promoters

N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.

N-Acylsulfonamide apoptosis promoters

N-Benzoyl arylsulfonamides having the formula Are BCL-X1 inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-X1 inhibiting compositions and methods of promoting apoptosis in a mammal.