40626-55-9 Usage
Amide derivative
A compound derived from a carboxylic acid by replacing the hydroxyl group (-OH) with an amide group (-NH2).
Two fluorine atoms attached to the acetamide group
The presence of two fluorine atoms in the acetamide group contributes to the compound's unique properties and potential pharmaceutical applications.
Chloride substituent on the phenyl ring
A chlorine atom attached to the phenyl ring, which can influence the compound's reactivity, stability, and biological activity.
Potential pharmaceutical applications
The compound has been studied for its potential use in the development of pharmaceutical drugs.
Antifungal agent
2-(4-Chloro-phenyl)-2,2-difluoro-acetamide has shown promise as an antifungal agent, which could be used to treat fungal infections.
Unique molecular structure
The compound's molecular structure, featuring a combination of different functional groups, contributes to its potential as a drug candidate.
Further research needed
Additional studies are required to fully understand the compound's biological activity and potential therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 40626-55-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,6,2 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40626-55:
(7*4)+(6*0)+(5*6)+(4*2)+(3*6)+(2*5)+(1*5)=99
99 % 10 = 9
So 40626-55-9 is a valid CAS Registry Number.
40626-55-9Relevant articles and documents
Direct Approach to 3-Fluoroindoles and 3,3-Difluoroindolines from 2,2-Difluoro-2-phenylethan-1-amines via C-H/N-H Coupling
Zhang, Lanfei,Zhang, Xiaofei,Cui, Yongmei,Yang, Chunhao
supporting information, p. 3815 - 3826 (2021/06/28)
Herein, a direct method for the synthesis of 3-fluoroindoles and 3,3-difluoroindolines from easily accessible 2,2-difluoro-2-phenyl ethan-1-amines is presented. This protocol was performed by Pd-catalyzed direct C-H/N-H coupling and employed picolinamide as a directing group. By controlling the temperature for this transformation, various 3,3-difluoroindolines and 3-fluoroindoles could be isolated with moderate to good yields.
