40637-44-3

Upstream product

• 19262-20-5 (1,2,2-Trimethyl-propyl)-benzene 
• 40637-42-1 4-(1-chloro-1,2,2-trimethylpropyl)nitrobenzene 
• 464-07-3 3,3-dimethyl-2-butanol 
• 71-43-2 benzene 

Downstream Products

• 50878-44-9 1-(3,3-dimethylbut-1-en-2-yl)-4-nitrobenzene 

Relevant academic research and scientific papers

Formation by SRN1 reactions and 1H N.M.R. properties of sterically encumbered 2,4,6-triaIkyIphenyl p-nitrobenzyl sulfides

Sterically hindered p-nitrobenzylic chlorides (1) and (2) react with the sodium salts of 2,4,6-trialkylbenzenethiols (3a)-(5a) by the SRN1 reaction to give good yields of the corresponding p-nitrobenzylic aryl sulfides (6)-(10). For example, th

STERIC AND ELECTRONIC LIMITATIONS OF THE SRN1 REACTION BETWEEN p-NITROBENZYLIC SUBSTRATES AND TERTIARY CARBANIONS

The SRN1 reaction between sterically hindered p-nitrobenzylic substrates and tertiary carbanions gives C-alkylated products whose yields depend on the steric bulk of both the benzylic substrate and the carbanion, and on the nature of the groups in the carbanion.