406476-31-1

Usage

Uses

Used in Pharmaceutical Drug Development:
5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID is used as a key intermediate in the synthesis of various pharmaceutical drugs due to its unique structure and functional groups. Its carboxylic acid group allows for easy derivatization and modification, enabling the development of new drug candidates with improved pharmacological properties.
Used in Medicinal Chemistry Research:
As a member of the bipyridine family, 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID is used as a research tool in medicinal chemistry to explore its potential biological activities and pharmacological effects. Its unique structure and functional groups make it an attractive target for studying its interactions with biological targets and evaluating its therapeutic potential.
Used in Drug Discovery:
The trifluoromethyl group present in 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID enhances the compound's lipophilicity and metabolic stability, making it a valuable tool in drug discovery. Its properties can be further optimized through chemical modifications, leading to the development of novel drug candidates with improved pharmacokinetic and pharmacodynamic profiles.
Used in Drug Delivery Systems:
5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID can be incorporated into drug delivery systems to improve the bioavailability and therapeutic efficacy of pharmaceutical drugs. Its unique structure and functional groups can be utilized to design targeted drug delivery systems, enhancing the compound's ability to reach specific tissues or cells and minimize side effects.
Used in Chemical Synthesis:
In addition to its applications in medicinal chemistry and drug development, 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID can also be used as a building block in the synthesis of various organic compounds. Its carboxylic acid group provides a reactive site for further chemical modifications, enabling the synthesis of new compounds with diverse applications in various industries.

InChI:InChI=1/C12H13F3N2O2/c13-12(14,15)9-1-2-10(16-7-9)17-5-3-8(4-6-17)11(18)19/h1-2,7-8H,3-6H2,(H,18,19)

Upstream product

• 420844-59-3 ethyl 1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylate 

Relevant academic research and scientific papers

1, 4-DISUBSTITUTED PIPERIDINES AS VASOPRESSIN RECEPTOR VIA ANTAGONISTS

The present invention provides compounds of formula (1) compositions comprising such compounds; the use of such compounds in therapy (such as in the treatment of dysmenorrhoea); and methods of treating patients with such compounds; wherein A and G are as defined herein.

TETRAHYDRO-NAPHTHALENE AND UREA DERIVATIVES

This invention relates to a hydroxy-tetrahydro-naphthalene or an urea derivative formula (I) and salts thereof which are useful as active ingredients of pharmaceutical preparations, wherein A represents formula (II) or (III) wherein # represents the connection position to the molecule and Q1a, Q2a, Q3a and Q4a are defined, and E represents formula (IV) or (V) wherein # represents the connection position to the molecule and Q1b, Q2b, Q3b, Q4b, Q5b, R1b, na, ma, Xa and Ra are defined.

PIPERIDINE/CYCLOHEXANE CARBOXAMIDE DERIVATIVES FOR USE AS VANILLOID RECEPTOR MODULATORS

Certain compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P', X, m and n are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition c