40661-10-7

Upstream product

• 110-95-2 N,N,N'N'-tetramethyl-1,3-propanediamine 
• 112-82-3 hexadecanyl bromide 
• 112-69-6 N,N-dimethylhexadecylamine 
• 109-64-8 1,3-dibromo-propane 

Relevant academic research and scientific papers

Vesicle Formation from Dimeric Surfactants through Ion-pairing. Adjustment for Polar Headgroup Separation leads to Control over Vesicular Thermotropic Properties

Eight new vesicle-forming dimeric surfactants are synthesized: the polar headgroup separation in such dimeric amphiphiles strongly influences their vesicular thermotropic phase-transition behaviour.

Influence of Amine-Based Cationic Gemini Surfactants on Catalytic Activity of α-Chymotrypsin

The α-chymotrypsin activity was tested in aqueous media with the presence of novel cationic amine–based gemini surfactant, with different spacer chain lengths and head group size, and also compared with the cationic cetyltrimethylammonium bromide (CTAB) a

Designing pH-sensitive gemini nanoparticles for non-viral gene delivery into keratinocytes

This study aimed to develop a more effective non-viral gene delivery system for keratinocyte transfection. To this end, gemini nanoparticles were formulated from plasmid DNA, the lipid DOPE (dioleoylphosphatidylethanolamine) and surfactants, where the sur

Micellization behavior of cationic gemini surfactants in aqueous-ethylene glycol solution

The micellization behavior of gemini surfactants i.e. alkanediyl-α, ω-bis(cetyldimethylammonium bromide) (C16-s-C 16,2Br- where s = 3, 4, 10) in 10% (v/v) ethylene glycol solution was investigated by surface tension and conductometric measurements at 300 K. The critical micelle concentration, degree of micellar ionization, surface excess concentration, minimum surface area per molecule of surfactant, surface pressure at the CMC and Gibbs energy of adsorption of the dimeric surfactants have also been determined in the presence of different salts (NaCl, NaBr and NaI). The critical micelle concentration and degree of micellar ionization values decrease significantly in the presence of sodium halides and follows the sequence NaCl NaBr NaI. The free energy, enthalpy and entropy of micellization of dimeric surfactants in 10% (v/v) ethylene glycol solution were determined using the temperature dependence of the critical micelle concentration. The standard free energy of micellization was found to be negative in all the cases. AOCS 2011.

Role of Spacer Chain Length in Dimeric Micellar Organization. Small Angle Neutron Scattering and Fluorescence Studies

Micelles of different dimeric amphiphiles Br(1-), n-C16H33NMe2(1+)-(CH2)m-N(1+)Me2-n-C16H33, Br(1-) (where m = 3, 4, 5, 6, 8, 10, and 12) adopt different morphologies and internal packing arrangements in aqueous media depending on their spacer chain length (m).Detailed measurements of small angle neutron scattering (SANS) cross sections from different bis-cationic, dimeric surfactant micelles in aqueous media (D2O) are reported.The data have been analyzed using the Hayter and Penfold model for macro ion solution to compute the interparticle structure factor S(Q) taking into account the screened Coulomb interactions between the dimeric micelles.The SANS analysis clearly indicated that the extent of aggregate growth and the variations of shapes of the dimeric micelles depend primarily on the spacer chain length.With spacer chain length, m/=4, the propensity of micellar growth was particularly pronounced.The effects of the variation of the concentration of dimeric surfactants with m = 5 and 10 on the SANS spectra and the effects of the temperature variation for the micellar system with m = 10 were also examined.The critical micelle concentrations (cmc) and their microenvironmental feature, namely, the microviscosities that the dimeric micellar aggregates offer to a solubilized, extrinsic fluorescence probe, 1,6-diphenyl-1,3,5-hexatriene, were also determined.The changes of cmcs and microviscosities as a function of spacer chain length have been explained in terms of conformational variations and progressive looping of the spacer in micellar core upon increasing m values.