406675-32-9Relevant academic research and scientific papers
An expedient synthesis of 6-arylpiperidine-2,4-diones by chain-extension of β-aryl-β-aminoacids
Leflemme, Nicolas,Dallemagne, Patrick,Rault, Sylvain
, p. 8997 - 8999 (2007/10/03)
The synthesis of novel 6-arylpiperidine-2,4-diones is described in five steps starting from β-aryl-β-aminoacids via the chain extension of the latter into δ-aryl-δ-amino-β-ketoacids. The chemical pathway involves an acylation of Meldrum's acid and yields useful building blocks for heterocyclic chemistry.
