21735-63-7 Usage
Description
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is a chemical compound with the molecular formula C11H10F3NO3. It is a white crystalline powder that is used as a pharmaceutical intermediate in the synthesis of various drugs. 3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is known for its ability to act as an inhibitor of fatty acid amide hydrolase (FAAH), an enzyme that is involved in the metabolism of endocannabinoids.
Uses
Used in Pharmaceutical Industry:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used as a pharmaceutical intermediate for the synthesis of various drugs. Its ability to inhibit fatty acid amide hydrolase (FAAH) makes it a potential candidate for the development of medications targeting pain, inflammation, and neurological disorders.
Used in Pain Management:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used as an analgesic agent for the treatment of pain. Its inhibition of FAAH leads to increased levels of endocannabinoids, which are known to play a role in pain modulation.
Used in Anti-Inflammatory Applications:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used as an anti-inflammatory agent. Its inhibition of FAAH can help reduce inflammation by modulating the endocannabinoid system.
Used in Neurological Disorder Treatment:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used as a potential treatment for neurological disorders. Its ability to modulate the endocannabinoid system may provide therapeutic benefits for conditions such as anxiety, depression, and neurodegenerative diseases.
Used in Anti-Cancer Research:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used in anti-cancer research for its potential anti-tumor properties. Studies are being conducted to explore its effectiveness in inhibiting the growth and progression of cancer cells.
Used in Anti-Inflammatory Research:
3-Phenyl-3-(2,2,2-trifluoroacetaMido)propanoic Acid is used in anti-inflammatory research to investigate its potential to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 21735-63-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,3 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21735-63:
(7*2)+(6*1)+(5*7)+(4*3)+(3*5)+(2*6)+(1*3)=97
97 % 10 = 7
So 21735-63-7 is a valid CAS Registry Number.
21735-63-7Relevant articles and documents
The kinetic resolution of oxazinones by alcoholysis: access to orthogonally protected β-amino acids
Cronin, Sarah A.,Connon, Stephen J.
supporting information, p. 7348 - 7352 (2021/09/07)
The catalytic, alcoholytic kinetic resolution of oxazinones is reported. A novel, stereochemically dense cinchona alkaloid-based catalyst can facilitate the highly enantiodiscriminatory (Sup to 101) ring-opening of oxazinones equipped with electrophilic aryl units to generate orthogonally protected β-amino acids for the first time.
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI)
Wu, Dongpei,Pontillo, Joseph,Ching, Brett,Hudson, Sarah,Gao, Yinghong,Fleck, Beth A.,Gogas, Kathleen,Wade, Warren S.
scheme or table, p. 4224 - 4227 (2009/04/10)
The design, synthesis, and SAR of a series of ring-constrained norepinephrine reuptake inhibitors are described. A substantially rigid inhibitor with potent functional activity at the transporter (IC50 = 8 nM) was used to develop a model for th
Efficient synthesis of 2-aryl-6-methyl-2,3-dihydro-1H-pyridin-4-ones
Renault, Olivier,Guillon, Jean,Dallemagne, Patrick,Rault, Sylvain
, p. 681 - 683 (2007/10/03)
Syntheses of 2-aryl-6-methyl-2,3-dihydro-1H-pyridin-4-ones were achieved starting from corresponding β-arylβ-amino acids. This reaction sequence involved, as a key step, the condensation of an acid chloride with a diketone using SmI3 as catalyst. A final intramolecular cyclization furnished the attempted product. (C) 2000 Elsevier Science Ltd.